HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → 4-Methoxy-benzo[a]phenazine-11-carboxylic Acid Methyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | 4-Methoxy-benzo[a]phenazine-11-carboxylic Acid | HCID 11120246 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-Methoxy-benzo[a]phenazine-11-carboxylic Acid Methyl Ester | HCID 69596857 | — |
Reaction Steps
Acetyl chloride (4.6 mL) was added dropwise to a suspension of 4-methoxy-benzo[a]phenazine-11-carboxylic acid (II.1, see Reference Example 1A, 4.9 g) in methanol (50 mL). The mixture was heated to reflux for 4 hours. The volatiles were then removed in vacuo to yield the title compound as a dark solid (quantitative yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07132419B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-145bfd4fba4d4104beae24ce0650b988 |
| Source note | uspto-grants-2006_11 |