Hydrochloric Acid → HCID 178483816, compound

Participants

Reaction Steps

To a solution of 3-methoxy-benzo[a]phenazine-11-carboxylic acid (2-dimethylamino-ethyl)-amide (170 mg) in dry N,N-dimethylformamide (3 mL) was added sodium thioethoxide (380 mg). The reaction mixture was then heated to reflux under argon for 3 hours. The reaction mixture was cooled, acidified (dilute HCl) and volatiles removed in vacuo. The residue was purified using column chromatography (20% methanol in dichloromethane) to yield the title compound as a red solid (142 mg).

Provenance & Evidence