Tetrabutylammonium Fluoride → HCID 10201240, compound

Participants

Reaction Steps

To a solution of 4-[2-(tert-butyl-dimethyl-silanyloxy)-ethoxy]-benzo[a]phenazine-11-carboxylic acid (2-dimethylamino-ethyl)-amide (125 mg) in tetrahydrofuran (5 mL) was added a 1.0M solution of tetrabutyl ammonium fluoride (1.2 mL). After stirring for 1.5 hours the reaction mixture was diluted with ethyl acetate, washed with water, dried (MgSO4) and the solvent removed in vacuo to yield crude product which was purified using flash chromatography to yield the title compound as an orange solid (24 mg).

Provenance & Evidence