HCID 69976512, compound → HCID 135532482, compound

HRID 719205Notes

Reaction equation

HRID 719205 reaction equation
[CH3:1][N:2]([CH3:31])[CH2:3][C@H:4]([NH:6][C:7]([C:9]1[C:22]2[C:13](=[N:14][C:15]3[C:20]([N:21]=2)=[C:19]2[CH:23]=[CH:24][CH:25]=[C:26]([O:27][CH3:28])[C:18]2=[CH:17][CH:16]=3)[CH:12]=[CH:11][C:10]=1[O:29]C)=[O:8])[CH3:5].[CH3:32][N:33]([CH3:63])[CH2:34][C@H:35]([NH:38][C:39]([C:41]1[C:54]2[C:45](=[N:46][C:47]3[C:52]([N:53]=2)=[C:51]2[CH:55]=[CH:56][CH:57]=[C:58]([O:59][CH3:60])[C:50]2=[CH:49][CH:48]=3)[CH:44]=[CH:43][C:42]=1[O:61]C)=[O:40])[CH2:36][OH:37]>>[CH3:31][N:2]([CH3:1])[CH2:3][C@H:4]([NH:6][C:7]([C:9]1[C:22]2[C:13](=[N:14][C:15]3[C:20]([N:21]=2)=[C:19]2[CH:23]=[CH:24][CH:25]=[C:26]([O:27][CH3:28])[C:18]2=[CH:17][CH:16]=3)[CH:12]=[CH:11][C:10]=1[OH:29])=[O:8])[CH3:5].[CH3:63][N:33]([CH3:32])[CH2:34][C@H:35]([NH:38][C:39]([C:41]1[C:54]2[C:45](=[N:46][C:47]3[C:52]([N:53]=2)=[C:51]2[CH:55]=[CH:56][CH:57]=[C:58]([O:59][CH3:60])[C:50]2=[CH:49][CH:48]=3)[CH:44]=[CH:43][C:42]=1[OH:61])=[O:40])[CH2:36][OH:37]

Participants

4

Reactant 2

HCID 69976512HCID 69976512, compoundHCID 86588784HCID 86588784, compound

Product 2

HCID 135532482HCID 135532482, compoundHCID 136330663HCID 136330663, compound

Procedure

10-Hydroxy-4-methoxy-benzo[a]phenazine-11-carboxylic acid (2-dimethylamino-1(R)-methyl-ethyl)-amide was prepared in an analogous manner from 4,10-dimethoxy-benzo[a]phenazine-11-carboxylic acid (2-dimethylamino-1(R)-methyl-ethyl)-amide; and 10-Hydroxy-4-methoxy-benzo[a]phenazine-11-carboxylic acid (2-dimethylamino-1(S)-hydroxymethyl-ethyl)-amide was prepared in an analogous manner from 4,10-dimethoxy-benzo[a]phenazine-11-carboxylic acid (2-dimethylamino-1(S)-hydroxymethyl-ethyl)-amide.

Sources & evidence

ORD record
ord-f4182102860547a8b2d2c9af93458be7
Source dataset
uspto-grants-2006_11
Patent number
US07132419B2

Reaction notes

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