HRID71924

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COC(=O)[C@@H]1C[C@H](C#N)CN1C(=O)OC(C)(C)C

HCID17750454

1-tert-Butyl 2-methyl (2S,4S)-4-cyanopyrrolidine-1,2-dicarboxylate

C12H18N2O4

结构：CC(C)(C)OC(=O)N1CCCC1C(=O)OCC(=O)c1ccc2cc(Br)ccc2c1

HCID66620206

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)N1CC(C#N)CC1C(=O)OCC(=O)c1ccc2cc(Br)ccc2c1

HCID66620420

未命名化合物

PROCEDURE

实验过程

Title compound was prepared according to the method employed to prepare pyrrolidine-1,2-dicarboxylic acid 2-[2-(6-bromo-naphthalen-2-yl)-2-oxo-ethyl]ester 1-tert-butyl ester in Example CL, substituting pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester with N-Boc-cis-4-cyano-L-proline methyl ester (643 mg, 67%)