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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 71925생성일: 2026년 10월 25일

2-(tert-Butoxycarbonyl)-2-azabicyclo[2.2.1]heptane-3-carboxylic acid → 3-[2-(4-Bromo-phenyl)-2-oxo-ethylcarbamoyl]-morpholine-4-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/71925

반응식

참여 물질

역할이름HCID투입량
반응물2-(tert-Butoxycarbonyl)-2-azabicyclo[2.2.1]heptane-3-carboxylic acidHCID 15056388—
반응물3-[2-(4-Bromo-phenyl)-2-oxo-ethylcarbamoyl]-2-aza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl esterHCID 59610686—
생성물3-[2-(4-Bromo-phenyl)-2-oxo-ethylcarbamoyl]-morpholine-4-carboxylic acid tert-butyl esterHCID 66620917—

반응 단계

Title compound was prepared according to the method employed to prepare 3-[2-(4-Bromo-phenyl)-2-oxo-ethylcarbamoyl]-2-aza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester (Example AE), substituting Morpholine-3,4-dicarboxylic acid 4-tert-butyl ester for 2-aza-bicyclo[2.2.1]heptane-2,3-dicarboxylic acid 2-tert-butyl ester.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08822430B2
출처 데이터셋uspto-grants-2014_09
ORD IDord-27791ed57d544c919df6bed3c5b28466
출처 메모uspto-grants-2014_09