m-Anisoyl chloride → HCID 178490486, compound

HRID 719268Notes

Reaction equation

HRID 719268 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:11]2[NH:15][N:14]=[C:13]([CH3:16])[C:12]=2[NH2:17])[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].[CH3:18][O:19][C:20]1[CH:21]=[C:22]([CH:26]=[CH:27][CH:28]=1)[C:23](Cl)=[O:24]>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:11]2[NH:15][N:14]=[C:13]([CH3:16])[C:12]=2[NH:17][C:23](=[O:24])[C:22]2[CH:26]=[CH:27][CH:28]=[C:20]([O:19][CH3:18])[CH:21]=2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10]

Participants

3

Reactant 2

HCID 74374m-Anisoyl chlorideHCID 178489090HCID 178489090, compound

Product 1

HCID 178490486HCID 178490486, compound

Procedure

The preparation took place in analogy with Example 15a), starting with 300 mg of 5-(3,4-dimethoxyphenyl)-3-methyl-1H-pyrazol-4-ylamine (44) and 242 mg of 3-methoxybenzoyl chloride. The following was obtained: 53

Workup

  1. customThe following was obtained

Sources & evidence

ORD record
ord-08541641d1c143d7b08382d714b668f3
Source dataset
uspto-grants-2006_11
Patent number
US07132428B2

Reaction notes

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