HCID 178438041, compound → HCID 178438040, compound

HRID 719279Notes

Reaction equation

HRID 719279 reaction equation
[CH2:1]([C:3]1[C:7]([N:8]=O)=[C:6]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[NH:5][N:4]=1)[CH3:2]>C(O)C.[Pd]>[NH2:8][C:7]1[C:3]([CH2:1][CH3:2])=[N:4][NH:5][C:6]=1[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

4

Reactant 1

HCID 178438041HCID 178438041, compound

Product 1

HCID 178438040HCID 178438040, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A solution of 6.3 g of 3-ethyl-4-nitroso-5-phenyl-1H-pyrazole in 220 mL of ethanol was treated with 2.0 g of 10% palladium/carbon catalyst and hydrogenated at RT and 50 psi for 16 h. The reaction mixture was filtered through celite and washed well with ethanol. The filtrate was concentrated to give the title compound as a brown oil.

Workup

  1. filtrationThe reaction mixture was filtered through celite
  2. washwashed well with ethanol
  3. concentrationThe filtrate was concentrated

Sources & evidence

ORD record
ord-22e167ee39984880a7ef6c9c47ccae1c
Source dataset
uspto-grants-2006_11
Patent number
US07132428B2

Reaction notes

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