反应详情

361 mg of 4-trifluoromethylbenzoyl chloride were added dropwise to a solution of 300 mg of 3-methyl-5-phenyl-1H-pyrazol-4-ylamine in 5 ml of pyridine at room temperature. The reaction mixture was stirred for 16 h and then concentrated. The residue was extracted into dichloromethane and washed with 0.5M hydrochloric acid, at which point the title compound precipitated.

1. concentrationconcentrated
2. extractionThe residue was extracted into dichloromethane
3. washwashed with 0.5M hydrochloric acid, at which
4. customprecipitated