2-Amino-4-phenylthiazole → HCID 10269781, compound

HRID 719307Notes

Reaction equation

HRID 719307 reaction equation
[NH2:1][C:2]1[S:3][CH:4]=[C:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[N:6]=1.[CH2:13]([C:16]1[CH:21]=[CH:20][C:19]([S:22](Cl)(=[O:24])=[O:23])=[CH:18][CH:17]=1)[CH2:14][CH3:15]>>[C:7]1([C:5]2[N:6]=[C:2]([NH:1][S:22]([C:19]3[CH:20]=[CH:21][C:16]([CH2:13][CH2:14][CH3:15])=[CH:17][CH:18]=3)(=[O:24])=[O:23])[S:3][CH:4]=2)[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1

Participants

3

Reactant 2

HCID 403022-Amino-4-phenylthiazoleHCID 27372224-N-Propylbenzenesulphonyl chloride

Product 1

HCID 10269781HCID 10269781, compound

Procedure

The title compound was prepared from 2-amino-4-phenylthiazole and 4-n-propylbenzenesulfonyl chloride as described in the synthetic METHOD B to give a white solid (29.8 mg) with purity >90%. MS (pos) m/z 359.2.

Sources & evidence

ORD record
ord-e8264ea9502549979921c3f7ee940ab3
Source dataset
uspto-grants-2006_11
Patent number
US07132436B2

Reaction notes

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