3-Chloro-2-methylbenzenesulfonyl chloride → HCID 10272954, compound

HRID 719310Notes

Reaction equation

HRID 719310 reaction equation
[NH2:1][C:2]1[S:3][CH:4]=[C:5]([C:7]2[CH:12]=[CH:11][CH:10]=[C:9]([N+:13]([O-:15])=[O:14])[CH:8]=2)[N:6]=1.[Cl:16][C:17]1[C:18]([CH3:27])=[C:19]([S:23](Cl)(=[O:25])=[O:24])[CH:20]=[CH:21][CH:22]=1>>[Cl:16][C:17]1[C:18]([CH3:27])=[C:19]([S:23]([NH:1][C:2]2[S:3][CH:4]=[C:5]([C:7]3[CH:12]=[CH:11][CH:10]=[C:9]([N+:13]([O-:15])=[O:14])[CH:8]=3)[N:6]=2)(=[O:25])=[O:24])[CH:20]=[CH:21][CH:22]=1

Participants

3

Reactant 2

HCID 5227343-Chloro-2-methylbenzenesulfonyl chlorideHCID 6135042-Amino-4-(3-nitrophenyl)thiazole

Product 1

HCID 10272954HCID 10272954, compound

Procedure

The title compound was prepared from 2-amino-4-(-3-nitrophenyl)thiazole and 3-chloro-2-methylbenzenesulfonyl chloride as described in the synthetic METHOD B to give a yellow solid (36.0 mg) with purity >90%. MS (pos) m/z 410.0.

Sources & evidence

ORD record
ord-da2b8dba4c8743adb5e8d9ad7c3d2d84
Source dataset
uspto-grants-2006_11
Patent number
US07132436B2

Reaction notes

Loading…