2-Amino-4-phenylthiazole → HCID 10155704, compound

HRID 719311Notes

Reaction equation

HRID 719311 reaction equation
[NH2:1][C:2]1[S:3][CH:4]=[C:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[N:6]=1.[Cl:13][C:14]1[C:15]([CH3:24])=[C:16]([S:20](Cl)(=[O:22])=[O:21])[CH:17]=[CH:18][CH:19]=1>>[Cl:13][C:14]1[C:15]([CH3:24])=[C:16]([S:20]([NH:1][C:2]2[S:3][CH:4]=[C:5]([C:7]3[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=3)[N:6]=2)(=[O:22])=[O:21])[CH:17]=[CH:18][CH:19]=1

Participants

3

Reactant 2

HCID 403022-Amino-4-phenylthiazoleHCID 5227343-Chloro-2-methylbenzenesulfonyl chloride

Product 1

HCID 10155704HCID 10155704, compound

Procedure

The title compound was prepared from 2-amino-4-phenylthiazole and 3-chloro-2-methylbenzenesulfonyl chloride as described in the synthetic METHOD B to give a white solid (51.8 mg) with purity >90%. MS (pos) m/z 365.1.

Sources & evidence

ORD record
ord-5d7bd6aaf787448ab836e4d305b0aae5
Source dataset
uspto-grants-2006_11
Patent number
US07132436B2

Reaction notes

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