2-Amino-4-phenylthiazole → HCID 10135537, compound

HRID 719317Notes

Reaction equation

HRID 719317 reaction equation
[NH2:1][C:2]1[S:3][CH:4]=[C:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[N:6]=1.[Cl:13][C:14]1[CH:19]=[C:18]([Cl:20])[CH:17]=[C:16]([CH3:21])[C:15]=1[S:22](Cl)(=[O:24])=[O:23]>>[Cl:13][C:14]1[CH:19]=[C:18]([Cl:20])[CH:17]=[C:16]([CH3:21])[C:15]=1[S:22]([NH:1][C:2]1[S:3][CH:4]=[C:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[N:6]=1)(=[O:24])=[O:23]

Participants

3

Reactant 2

HCID 403022-Amino-4-phenylthiazoleHCID 28013872,4-Dichloro-6-methylbenzenesulfonyl chloride

Product 1

HCID 10135537HCID 10135537, compound

Procedure

The title compound was prepared from 2-amino-4-phenylthiazole and 2,4-dichloro-6-methylbenzenesulfonyl chloride as described in the synthetic METHOD B to give a white solid (49.2 mg) with purity >90%. MS (pos) m/z 399.1,401.1.

Sources & evidence

ORD record
ord-a91d510d4cc044d28346b19c3081dac5
Source dataset
uspto-grants-2006_11
Patent number
US07132436B2

Reaction notes

Loading…