4-(3-Pyridinyl)-2-thiazolamine → HCID 9947291, compound

HRID 719324Notes

Reaction equation

HRID 719324 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[N:8]=[C:9]([NH2:12])[S:10][CH:11]=2)[CH:2]=1.[Cl:13][C:14]1[C:15]([CH3:24])=[C:16]([S:20](Cl)(=[O:22])=[O:21])[CH:17]=[CH:18][CH:19]=1>>[Cl:13][C:14]1[C:15]([CH3:24])=[C:16]([S:20]([NH:12][C:9]2[S:10][CH:11]=[C:7]([C:3]3[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=3)[N:8]=2)(=[O:22])=[O:21])[CH:17]=[CH:18][CH:19]=1

Participants

3

Reactant 2

HCID 1548934-(3-Pyridinyl)-2-thiazolamineHCID 5227343-Chloro-2-methylbenzenesulfonyl chloride

Product 1

HCID 9947291HCID 9947291, compound

Procedure

The title compound was prepared from 4-(3-pyridyl)-1,3-thiazol-2-amine and 3-chloro-2-methylbenzenesulfonyl chloride as described in the synthetic METHOD B to give a yellow solid (21.4 mg) with purity >90%. MS (pos) m/z 366.1.

Sources & evidence

ORD record
ord-5a71de44a13a4e1db719d3373bf3bb10
Source dataset
uspto-grants-2006_11
Patent number
US07132436B2

Reaction notes

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