HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-2-methylbenzenesulfonyl chloride → HCID 10181978, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-2-methylbenzenesulfonyl chloride | HCID 522734 | — |
| Reactant | 4-(2-chloro-5-nitrophenyl)-1,3-thiazol-2-amine hydrobromide | HCID 2777361 | — |
| Product | HCID 10181978 | HCID 10181978 | — |
Reaction Steps
The title compound was prepared from 4-(2-chloro-5-nitrophenyl)-1,3-thiazol-2-amine hydrobromide and 3-chloro-2-methylbenzenesulfonyl chloride as described in the synthetic METHOD B to give a yellow solid (16.5 mg) with purity >90%. 1H-NMR (DMSO-d6) δ 13.43 (s, NH), 8.46 (d, J=2.8 Hz, 1 H), 8.29 (d, J=2.8 Hz, 1 H), 7.96 (dd, J=1.1 Hz, J=8.0 Hz, 1 H), 7.90 (d, J=8.8 Hz, 1 H), 7.70 (dd, J=1.1 hz, J=8.0 Hz, 1 H), 7.42 (t, J=8.0 Hz, 1 H), 7.52 (s, 1 H), 2.67 (s, 3 H); MS (pos) m/z 442.2,444.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07132436B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-3b7e28f3a28d4b4c831bf4dc71752125 |
| Source note | uspto-grants-2006_11 |