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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 719329Generated: October 25, 2026

4-(3-Pyridinyl)-2-thiazolamine → 2,4,6-Trichloro-N-[4-(3-pyridinyl)-1,3-thiazol-2-yl]benzenesulfonamide

https://huagongshe.com/reaction/719329

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(3-Pyridinyl)-2-thiazolamineHCID 154893—
Reactant2,4,6-Trichlorobenzenesulfonyl chlorideHCID 521335—
Product2,4,6-Trichloro-N-[4-(3-pyridinyl)-1,3-thiazol-2-yl]benzenesulfonamideHCID 10136952—

Reaction Steps

The title compound was prepared from 4-(3-pyridyl)-1,3-thiazol-2-amine and 2,4,6-trichlorobenzenesulfonyl chloride as described in the synthetic METHOD B to give a yellow solid (29.3 mg) with purity >90%: MS (pos) m/z 422.1; HRMS m/z 418.9134 (calc. of monoisotopic mass for C14H8Cl3N3O2S2 gives 418.9123).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07132436B2
Source datasetuspto-grants-2006_11
ORD IDord-f6ee2e41f3e4460f9237787acfbcc012
Source noteuspto-grants-2006_11