HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(4-(2-Amino-1,3-thiazol-4-yl)phenyl)acetamide → N-[4-(2-{[(2,4-dichloro-6-methylphenyl)sulfonyl]amino}-1,3-thiazol-4-yl)phenyl]acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(4-(2-Amino-1,3-thiazol-4-yl)phenyl)acetamide | HCID 519881 | — |
| Reactant | 2,4-Dichloro-6-methylbenzenesulfonyl chloride | HCID 2801387 | — |
| Product | N-[4-(2-{[(2,4-dichloro-6-methylphenyl)sulfonyl]amino}-1,3-thiazol-4-yl)phenyl]acetamide | HCID 10276064 | — |
Reaction Steps
The title compound was prepared N-[4-(2-amino-1,3-thiazol-4-yl)phenyl]acetamide and 2,4-dichloro-6-methylbenzenesulfonyl chloride as described in the synthetic METHOD B to give a white-yellow solid (8.1 mg) with purity >80%. MS (pos) m/z 456.2, 458.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07132436B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-62d8e2819ebd444c889d6c24645dca44 |
| Source note | uspto-grants-2006_11 |