化工社化工社 化学情報印刷レポート · 研究参考用
4-(2-Chlorophenyl)-1,3-thiazol-2-amine → 4,5-Dichloro-N-[4-(2-chlorophenyl)-1,3-thiazol-2-yl]-2-thiophenesulfonamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-(2-Chlorophenyl)-1,3-thiazol-2-amine | HCID 224764 | — |
| 反応物 | 4,5-Dichlorothiophene-2-sulfonyl chloride | HCID 518622 | — |
| 生成物 | 4,5-Dichloro-N-[4-(2-chlorophenyl)-1,3-thiazol-2-yl]-2-thiophenesulfonamide | HCID 10137247 | — |
反応手順
The title compound was prepared from 4-(2-chlorophenyl)-1,3-thiazol-2-amine (57 mg) and 2,3-dichlorothiophene-5-sulfonyl chloride (68 mg) as described in the synthetic METHOD B to give a white solid (56.6 mg) with purity >90%: MS (pos) m/z 425.3, 427.3; HRMS m/z 423.8737 (calc. of monoisotopic mass for C13 H7 Cl3 N2 O2 S3 gives 423.8735).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07132436B2 |
| 出典データセット | uspto-grants-2006_11 |
| ORD ID | ord-62bfaf63b74d473db71d07d3163cd4f5 |
| 出典メモ | uspto-grants-2006_11 |