4-N-Propylbenzenesulphonyl chloride → HCID 21898211, compound

HRID 719372Notes

Reaction equation

HRID 719372 reaction equation
[Cl:1][C:2]1[S:3][C:4]([S:15]([CH3:18])(=[O:17])=[O:16])=[C:5]2[C:10]3[N:11]=[C:12]([NH2:14])[S:13][C:9]=3[CH2:8][CH2:7][C:6]=12.[CH2:19]([C:22]1[CH:27]=[CH:26][C:25]([S:28](Cl)(=[O:30])=[O:29])=[CH:24][CH:23]=1)[CH2:20][CH3:21]>>[Cl:1][C:2]1[S:3][C:4]([S:15]([CH3:18])(=[O:17])=[O:16])=[C:5]2[C:10]3[N:11]=[C:12]([NH:14][S:28]([C:25]4[CH:26]=[CH:27][C:22]([CH2:19][CH2:20][CH3:21])=[CH:23][CH:24]=4)(=[O:30])=[O:29])[S:13][C:9]=3[CH2:8][CH2:7][C:6]=12

Participants

3

Reactant 2

HCID 27372224-N-Propylbenzenesulphonyl chlorideHCID 21898198HCID 21898198, compound

Product 1

HCID 21898211HCID 21898211, compound

Procedure

The title compound was prepared from 6-chloro-8-(methylsulfonyl)-4,5-dihydrothieno[3,4-e][1,3]benzothiazol-2-amine (61 mg, synthesized according to METHOD I from 1-chloro-3-(methylsulfonyl)-4,5,6,7-tetrahydrobenzo-[c]thiophen-4-one) and 4-n-propylbenzenesulfonyl chloride (46 mg) as described in the synthetic METHOD A to give a white powder (18 mg) with a purity of 90%: MS-ES (pos) m/z 501.2.

Sources & evidence

ORD record
ord-d6be3c9f8ecc453ab617c7e24618275c
Source dataset
uspto-grants-2006_11
Patent number
US07132436B2

Reaction notes

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