(1,1'-Biphenyl)-4-sulphonyl chloride → HCID 11408633, compound

HRID 719377Notes

Reaction equation

HRID 719377 reaction equation
[N+:1]([C:4]1[CH:17]=[C:16]2[C:7]([CH2:8][CH2:9][C:10]3[S:14][C:13]([NH2:15])=[N:12][C:11]=32)=[CH:6][CH:5]=1)([O-:3])=[O:2].[C:18]1([C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[CH:23]=[CH:22][C:21]([S:24](Cl)(=[O:26])=[O:25])=[CH:20][CH:19]=1>>[N+:1]([C:4]1[CH:17]=[C:16]2[C:7]([CH2:8][CH2:9][C:10]3[S:14][C:13]([NH:15][S:24]([C:21]4[CH:20]=[CH:19][C:18]([C:28]5[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=5)=[CH:23][CH:22]=4)(=[O:26])=[O:25])=[N:12][C:11]=32)=[CH:6][CH:5]=1)([O-:3])=[O:2]

Participants

3

Reactant 2

HCID 74192(1,1'-Biphenyl)-4-sulphonyl chlorideHCID 9992165HCID 9992165, compound

Product 1

HCID 11408633HCID 11408633, compound

Procedure

The title compound was prepared from 8nitro-4,5-dihydronaphtho[1,2-d][1,3]thiazol-2-amine (100 mg, synthesized according to METHOD I from 7-nitrotetralone) and 4-biphenylsulfonyl chloride (122 mg) as described in the synetic METHOD A to give a yellow powder (4.4 mg) with a purity of >90%: MS-ES (neg) m/z 462.4.

Sources & evidence

ORD record
ord-2d1696ed5b3d4772be1e1e67329cfea7
Source dataset
uspto-grants-2006_11
Patent number
US07132436B2

Reaction notes

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