Isopropylamine → HCID 21899882, compound

Participants

Reaction Steps

Isopropylamine (0.78 g) was added to an acetonitrile solution (10 mL) of 3-methanesulfonyloxyphthalic anhydride (1.60 g) under ice cooling and the mixture was further stirred at room temperature for 8 hours. After finishing the reaction, the solvent and the excess of isopropylamine were distilled off under reduced pressure and the obtained crude product was washed with a small amount of acetonitrile to obtain N-isopropyl-3-methanesulfonyloxyphthalamic acid (1.80 g) having the melting point of 56–59° C.

Provenance & Evidence