3,4-Diaminobenzoic acid → HCID 178513575, compound

Participants

Reaction Steps

2-{4-[2-(4-Chloro-phenyl)-[1,3]dioxolan-2-yl]-phenyl}-1H-benzoimidazole-5-carboxylic acid. This compound was prepared as described in Example 1 Step C from 4-[2-(4-chloro-phenyl)-[1,3]dioxolan-2-yl]-benzaldehyde (100 mg, 0.34 mmol) and 3,4-diamino-benzoic acid (53 mg, 0.34 mmol). The title compound was obtained as a tan solid 135 mg (92%). MS (ESI): mass calculated for C23H17ClN2O4, 420.1; m/z found, 421.1 [M+H]+, 419.1 [M−H]−. HPLC (Method B): Rt=2.43.

Provenance & Evidence