HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-Imidazole-1-propanamine → 2-Chloro-5-[3-[[3-(1H-imidazol-1-yl)propyl]amino]propyl]-N-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-Imidazole-1-propanamine | HCID 78736 | — |
| Reactant | chloro-5-[3-[(methylsulfonyl)oxy]propyl]-N-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-benzamide | HCID 12988688 | — |
| Product | 2-Chloro-5-[3-[[3-(1H-imidazol-1-yl)propyl]amino]propyl]-N-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)benzamide | HCID 10298800 | — |
Reaction Steps
Synthesized from 2-chloro-5-[3-[(methylsulfonyl)oxy]propyl]-N-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-benzamide (Example 6e, 1 mg,) and 1-(3-aminopropyl)imidazole according to the procedure described in Example 6f to afford the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07132457B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-3e86e0c8690c44a28207069d626cd129 |
| Source note | uspto-grants-2006_11 |