Phenol → HCID 69203134, compound

HRID 720154Notes

Reaction equation

HRID 720154 reaction equation
[C:1]([O:5][C:6]([NH:8][C@H:9]([CH2:13][O:14][C:15]1[CH:20]=[CH:19][C:18](F)=[CH:17][CH:16]=1)[C:10]([OH:12])=[O:11])=[O:7])([CH3:4])([CH3:3])[CH3:2].C1(O)C=CC=CC=1.FC1C=CC(O)=CC=1>>[C:1]([O:5][C:6]([NH:8][C@H:9]([CH2:13][O:14][C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1)[C:10]([OH:12])=[O:11])=[O:7])([CH3:4])([CH3:2])[CH3:3]

Participants

4

Reactant 3

HCID 996PhenolHCID 97324-FluorophenolHCID 58736947HCID 58736947, compound

Product 1

HCID 69203134HCID 69203134, compound

Procedure

(2R)-2-tert-Butoxycarbonylamino-3-(phenoxy)-propionic acid was prepared analogously to (2R)-2-tert-Butoxycarbonylamino-3-(4-fluoro-phenoxy)-propionic acid of example 263 except that phenol was substituted for 4-fluorophenol.

Sources & evidence

ORD record
ord-502507edf1aa4cb19d9ab148f050246e
Source dataset
uspto-grants-2006_11
Patent number
US07132533B2

Reaction notes

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