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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 720192Generated: October 29, 2026

Trifluoroacetic acid → HCID 21901708, compound

https://huagongshe.com/reaction/720192

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 21901751HCID 21901751—
SolventDichloromethaneHCID 6344—
ProductHCID 21901708HCID 21901708—

Reaction Steps

2-Allyl-4-benzyloxy-pyrrolidine-1-carboxylic acid tert-butyl ester, 51, (0.76 g, 2.4 mmol) is dissolved in methylene chloride (33 mL), and trifluoroacetic acid (25 mL) is added. The reaction mixture is stirred for 1 hour and then concentrated in vacuo. MeOH (40 mL) is added and the solvent is removed in vacuo to afford the desired product in approximately quanitative yield as a viscous oil which is used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07132539B2
Source datasetuspto-grants-2006_11
ORD IDord-afea64692fb74b62a91960ed6973c908
Source noteuspto-grants-2006_11