Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 1-Fluoro-3-nitrobenzene | HCID 9823 | — |
| Reactant | 2-Morpholinoethylamine | HCID 408285 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 21889081 | HCID 21889081 | — |
Reaction Steps
28.2 g 3-fluoronitrobenzene and 143 g 4-(2-aminoethyl)morpholine were dissolved in 300 ml dimethyl sulfoxide, and the batch was stirred for 60 h at 100° C. After cooling, the batch was poured into 1 l water. The mixture was extracted several times with methyl tert-butyl ether, and the combined organic phases were reduced to dryness in a rotary evaporator, yielding a dark liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07135047B2 |
|---|
| Source dataset | uspto-grants-2006_11 |
|---|
| ORD ID | ord-e3e0980e9aca46d2a33d904211093112 |
|---|
| Source note | uspto-grants-2006_11 |
|---|
