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HRID720245

反应详情

EQUATION

反应方程式

HRID 720245 的结构方程式

REACTANTS

反应物

2
结构：CC1(S(N)(=O)=O)CC1
HCID21889814

1-Methylcyclopropane-1-sulfonamide

C4H9NO2S

结构：CC(C)(C)NS(=O)(=O)C1(C(=O)c2ccccc2)CC1
HCID21889830

1-Benzoyl-N-tert-butylcyclopropane-1-sulfonamide

C14H19NO3S

PRODUCTS

生成物

1
结构：NS(=O)(=O)C1(C(=O)c2ccccc2)CC1
HCID21889794

1-Benzoylcyclopropane-1-sulfonamide

C10H11NO3S

收率 87%

PROCEDURE

实验过程

This compound, Example 6,1-benzoylcyclopropyl-sulfonamide, was obtained in 87% yield from N-tert-butyl(1-benzoyl)cyclopropylsul-fonamide using the procedure described for the synthesis of 1-Methylcyclopropylsulfonamide, followed by recrystallization from the minimum amount of EtOAc in hexane: 1H NMR (DMSO-d6) δ 1.39 (m, 2H), 1.61 (m, 2H), 7.22 (s, 2H), 7.53 (t, J=7.6 Hz, 2H), 7.65 (t, J=7.6 Hz, 1H), 8.06 (d, J=8.2 Hz, 2H); 13C NMR (DMSO d6) δ 12.3, 48.4, 128.1, 130.0, 133.4, 135.3, 192.0.

WORKUP

后处理

  1. customfollowed by recrystallization from the minimum amount of EtOAc in hexane