3-(2-Fluorophenyl)prop-2-enoic acid → HCID 69356010, compound

HRID 720269Notes

Reaction equation

HRID 720269 reaction equation
[F:1][C:2]1[CH:12]=[CH:11][CH:10]=[CH:9][C:3]=1[CH:4]=[CH:5][C:6]([OH:8])=O.[S:13]1[CH:17]=[CH:16][N:15]=[C:14]1[C:18]1[CH:19]=[C:20]([C@@H:24]([NH2:26])[CH3:25])[CH:21]=[CH:22][CH:23]=1>>[F:1][C:2]1[CH:12]=[CH:11][CH:10]=[CH:9][C:3]=1[CH:4]=[CH:5][C:6]([NH:26][C@H:24]([C:20]1[CH:21]=[CH:22][CH:23]=[C:18]([C:14]2[S:13][CH:17]=[CH:16][N:15]=2)[CH:19]=1)[CH3:25])=[O:8]

Participants

3

Reactant 2

HCID 679773-(2-Fluorophenyl)prop-2-enoic acidHCID 58739159HCID 58739159, compound

Product 1

HCID 69356010HCID 69356010, compound

Procedure

The title compound was prepared from 2-fluorocinnamic acid and (S)-1-(3-thiazol-2-yl-phenyl)-ethylamine following the general procedures as described for Example 1.

Sources & evidence

ORD record
ord-6d6df2f3d86d44329549f181ca7e0062
Source dataset
uspto-grants-2006_11
Patent number
US07135472B2

Reaction notes

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