Trifluoroacetic acid → Trifluoroacetic acid

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Reaction Steps

5-Benzyloxy-2-(4-methanesulfonyl-piperazin-1-yl)-1-methyl-6-oxo-1,6-dihydro-pyrimidine-4-carboxylic acid ethyl ester (0.22 g, 0.49 mmol) was treated with TFA to yield the title compound as a brown oily TFA salt (0.1564 g). 1H NMR (500 MHz, CDCl3) δ: 4.45 (2H, q, J=7.1 Hz), 3.59 (3H, s), 3.42–3.39 (4H, m), 3.28–3.26 (4H, m), 2.86 (3H, s), 1.42 (3H, t, J=7.0 Hz). HRMS (M−H) calcd for C13H19N4O6S: 359.10253. found: 359.1039.

Provenance & Evidence