Ethyl 3-(5,6,7-trimethoxynaphthalen-2-yl)propenoate → Ethyl 3-(5,6,7-trimethoxynaphthalen-2-yl)propionate

HRID 720314Notes

Reaction equation

HRID 720314 reaction equation
[CH3:1][O:2][C:3]1[C:12]([O:13][CH3:14])=[C:11]([O:15][CH3:16])[CH:10]=[C:9]2[C:4]=1[CH:5]=[CH:6][C:7]([CH:17]=[CH:18][C:19]([O:21][CH2:22][CH3:23])=[O:20])=[CH:8]2>CO.[Pd]>[CH3:1][O:2][C:3]1[C:12]([O:13][CH3:14])=[C:11]([O:15][CH3:16])[CH:10]=[C:9]2[C:4]=1[CH:5]=[CH:6][C:7]([CH2:17][CH2:18][C:19]([O:21][CH2:22][CH3:23])=[O:20])=[CH:8]2

Participants

4

Reactant 1

HCID 68436859Ethyl 3-(5,6,7-trimethoxynaphthalen-2-yl)propenoate

Product 1

HCID 21891562Ethyl 3-(5,6,7-trimethoxynaphthalen-2-yl)propionate

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

Ethyl 3-(5,6,7-trimethoxynaphthalen-2-yl)propenoate (1.70 g) was dissolved in methanol (20 mL), 10% palladium on carbon (510 mg) was added to the solution, and the mixture was stirred at room temperature for 2.5 hours under a hydrogen atmosphere. The reaction mixture was filtered, and the filtrate was then concentrated to obtain the title compound.

Workup

  1. filtrationThe reaction mixture was filtered
  2. concentrationthe filtrate was then concentrated

Sources & evidence

ORD record
ord-e4ed9e3832cb4c1487d01545afa9113b
Source dataset
uspto-grants-2006_11
Patent number
US07135473B2

Reaction notes

Loading…