Hexahydro-1,4-diazepine → HCID 21891656, compound

HRID 720351Notes

Reaction equation

HRID 720351 reaction equation
Cl[CH2:2][C:3]1[N:7]([CH3:8])[C:6]2[C:9]([O:17][CH3:18])=[C:10]([O:15][CH3:16])[C:11]([O:13][CH3:14])=[CH:12][C:5]=2[N:4]=1.[NH:19]1[CH2:25][CH2:24][CH2:23][NH:22][CH2:21][CH2:20]1>>[CH3:8][N:7]1[C:6]2[C:9]([O:17][CH3:18])=[C:10]([O:15][CH3:16])[C:11]([O:13][CH3:14])=[CH:12][C:5]=2[N:4]=[C:3]1[CH2:2][N:19]1[CH2:25][CH2:24][CH2:23][N:22]([CH2:2][C:3]2[N:7]([CH3:8])[C:6]3[C:9]([O:17][CH3:18])=[C:10]([O:15][CH3:16])[C:11]([O:13][CH3:14])=[CH:12][C:5]=3[N:4]=2)[CH2:21][CH2:20]1

Participants

3

Reactant 2

HCID 68163Hexahydro-1,4-diazepineHCID 21891566HCID 21891566, compound

Product 1

HCID 21891656HCID 21891656, compound

Procedure

2-Chloromethyl-1-methyl-5,6,7-trimethoxy-benzimidazole (39 mg) and homopiperazine (7 mg) were reacted in the same manner as in Example 1 to obtain the title compound as a free base.

Sources & evidence

ORD record
ord-a32f37f5d7d84a8a89b2f2ef02eebd39
Source dataset
uspto-grants-2006_11
Patent number
US07135473B2

Reaction notes

Loading…