Hexahydro-1,4-diazepine → HCID 21891652, compound

HRID 720362Notes

Reaction equation

HRID 720362 reaction equation
Br[CH2:2][CH2:3][CH2:4][C:5]1[S:6][C:7]2[C:13]([O:14][CH3:15])=[C:12]([O:16][CH3:17])[C:11]([O:18][CH3:19])=[CH:10][C:8]=2[N:9]=1.[NH:20]1[CH2:26][CH2:25][CH2:24][NH:23][CH2:22][CH2:21]1>>[CH3:19][O:18][C:11]1[C:12]([O:16][CH3:17])=[C:13]([O:14][CH3:15])[C:7]2[S:6][C:5]([CH2:4][CH2:3][CH2:2][N:20]3[CH2:26][CH2:25][CH2:24][N:23]([CH2:2][CH2:3][CH2:4][C:5]4[S:6][C:7]5[C:13]([O:14][CH3:15])=[C:12]([O:16][CH3:17])[C:11]([O:18][CH3:19])=[CH:10][C:8]=5[N:9]=4)[CH2:22][CH2:21]3)=[N:9][C:8]=2[CH:10]=1

Participants

3

Reactant 2

HCID 68163Hexahydro-1,4-diazepineHCID 21891609HCID 21891609, compound

Product 1

HCID 21891652HCID 21891652, compound

Procedure

2-(3-Bromopropyl)-5,6,7-trimethoxybenzothiazole (444 mg) and homopiperazine (64 mg) were reacted in the same manner as in Example 1 to obtain the title compound as a free base.

Sources & evidence

ORD record
ord-63c0b08e0b254a7ea8a2d73f32b08b2d
Source dataset
uspto-grants-2006_11
Patent number
US07135473B2

Reaction notes

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