Phenacyl bromide → HCID 21892156, compound

Participants

Reaction Steps

1-(Phenacyl)-5,6,7,8-tetrahydro-quinolinium bromide: The title compound was prepared from 2-bromo-1-phenyl-ethanone (507.7 mg, 2.55 mmol), 5,6,7,8-tetrahydro-quinoline (275 μL, 2.13 mmol) and acetonitrile (4.2 mL), similar to Example 1a, and yielded 694 mg (98%) as a light tan solid. 1H NMR (DMSO-d6): 8.80 (d, J=6.05 Hz, 1H), 8.45 (d, J=7.70 Hz, 1H), 8.11 (d, J=7.97 Hz, 2H), 8.00 (dd, J=7.69, 6.31 Hz, 1H), 7.82 (t, J=7.42 Hz, 1H), 7.68 (t, J=7.56 Hz, 1H), 6.52 (s, 2H), 3.02 (t, J=6.18 Hz, 2H), 2.92 (t, J=6.18 Hz, 2H), 1.85 (m, 2H), 1.77 (m, 2H).

Provenance & Evidence