Acrylonitrile → HCID 10022323, compound

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Reaction Steps

The title compound was prepared from 1-(3-bromo-phenacyl)-quinolinium bromide (150 mg, 0.368 mmol), tetrapyridinecobalt(II) dichromate (306 mg, 0.502 mmol), sodium bicarbonate (96.3 mg, 1.15 mmol), acrylonitrile (150 μL, 2.28 mmol), and N,N-dimethylformamide (4.0 mL), similar to Example 1b, and yielded 21.2 mg (15%) as a yellow solid. 1H NMR (CDCl3): 8.20 (t, J=1.79 Hz, 1H), 8.06 (d, J=8.51 Hz, 1H), 7.98 (dt, J=6.25, 1.38 Hz, 1H), 7.86 (dd, J=7.83, 1.51 Hz, 1H), 7.81 (ddd, J=6.52, 2.06, 0.96 Hz, 1H), 7.76 (d, J=9.06 Hz, 1H), 7.69 (d, J=9.06 Hz, 1H), 7.63 (ddd, J=8.31, 7.14, 1.65 Hz, 1H), 7.56 (td, J=7.41, 1.10 Hz, 1H), 7.45 (t, J=7.83 Hz, 1H), 7.44 (s, 1H).

Provenance & Evidence