Acrylonitrile → HCID 11723894, compound

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Reaction Steps

The title compound was prepared from 1-(4-methoxy-phenacyl)-quinolinium bromide (110 mg, 0.307 mmol), tetrapyridinecobalt(II) dichromate (202 mg, 0.332 mmol), sodium bicarbonate (66.2 mg, 0.788 mmol), acrylonitrile (110 μL, 1.67 mmol), and N,N-dimethylformamide (2.0 mL), similar to Example 1b, and yielded 26.6 mg (26%) as a yellow solid. 1H NMR (CDCl3): 8.08 (dd, J=9.15, 2.20 Hz, 2H), 8.02 (d, J=8.52 Hz, 1H), 7.83 (dd, J=7.55, 1.78 Hz, 1H), 7.70 (d, J=9.34 Hz, 1H), 7.66 (d, J=9.06 Hz, 1H), 7.59 (td, J=7.83, 1.83 Hz, 1H), 7.52 (td, J=7.48, 1.19 Hz, 1H), 7.38 (s, 1H), 7.05 (dd, J=9.25, 2.33 Hz, 2H), 3.94 (s, 3H).

Provenance & Evidence