Acrylonitrile → HCID 10337357, compound

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Reaction Steps

The title compound was prepared from 1-(4-nitro-phenacyl)-quinolinium bromide (119 mg, 0.319 mmol), tetrapyridinecobalt(II) dichromate (205 mg, 0.336 mmol), sodium bicarbonate (68.3 mg, 0.813 mmol), acrylonitrile (100 μL, 1.52 mmol), and N,N-dimethylformamide (2.0 mL), similar to Example 1b, and yielded 55.0 mg (50%) as a yellow solid. 1H NMR (CDCl3): 8.43 (dd, J=9.07, 2.20 Hz, 2H), 8.21 (dd, J=8.88, 2.13 Hz, 2H), 8.12 (d, J=8.52 Hz, 1H), 7.89 (dd, J=7.70, 1.64 Hz, 1H), 7.82 (d, J=9.07 Hz, 1H), 7.71 (d, J=9.06 Hz, 1H), 7.67 (ddd, J=8.17, 7.08, 1.58 Hz, 1H), 7.59 (td, J=7.49, 1.10 Hz, 1H), 7.44 (s, 1H).

Provenance & Evidence