7-Methylquinoline → HCID 21892120, compound

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Reaction Steps

1-[2-(4-Fluoro-phenyl)-2-oxo-ethyl]-7-methyl-quinolinium bromide: The title compound was prepared from 2-bromo-(4-fluoro-phenyl) ethanone (0.352 g, 2.46 mmol) and 7-methyl-quinoline (0.71 g, 3.27 mmol), by a method similar to that described for the preparation of Example 1a, and yielded 0.741 g (84%). 1H NMR (DMSO-d6): 9.42 (dd, J=16.2, 5.7 Hz, 2H), 8.44 (d, J=8.4 Hz, 1H), 8.35 (s, 1H), 8.24 (m, 3H), 7.92 (d, J=8.4 Hz, 1H), 7.56 (m, 2H), 6.95 (s, 2H), 2.60 (s, 3H).

Provenance & Evidence