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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 720423Generated: October 29, 2026

Imidazole → HCID 21892172, compound

https://huagongshe.com/reaction/720423

Reaction equation

Participants

RoleNameHCIDCharge
ReactantImidazoleHCID 795—
ReactantHCID 21892120HCID 21892120—
ProductHCID 21892172HCID 21892172—

Reaction Steps

The title compound was prepared as described for Example 21, using 3-cyano-1-(4-fluoro-benzoyl)-8-methyl-pyrrolo[1,2-a]quinoline (54 mg, 0.164 mmol) and imidazole, and yielded 50.1 mg (81%). 1H NMR (CDCl3): 8.20 (dt, J=8.7, 2.1 Hz, 2H), 8.04 (s, broad, 1H), 7.89 (m, 1H), 7.74 (m, 2H), 7.62 (m, 3H), 7.44 (m, 2H), 7.43 (s, broad, 1H), 7.39 (dd, J=7.8, 0.6 Hz, 1H), 7.30 (s, broad, 1H), 2.54 (s, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07135480B2
Source datasetuspto-grants-2006_11
ORD IDord-35a9878a67eb4fbdb30770cdd93b7bd9
Source noteuspto-grants-2006_11