HCID 10042094, compound → HCID 10065140, compound

Participants

Reaction Steps

A mixture of 3-cyano-1-(4-methoxy-benzoyl)-pyrrolo[1,2-a]quinoxaline (14.5 mg, 0.0044 mmol) in 10 mL of methanol and 0.5 mL acetone was hydrogenated on PtO2 at 40 psi for 4 h. The reaction mixture was filtered, concentrated under vacuum and the residue was purified by chromatography (25% ethyl acetate/hexane) to yield 7.2 mg (50%) of the title compound. 1H NMR (CDCl3): 7.97 (m, 2H), 6.97 (m, 7H), 4.48 (s, 2H), 4.25 (s, broad, 1H), 3.92 (s, 3H).

Provenance & Evidence