Hydrochloric Acid → HCID 10404977, compound

Participants

Reaction Conditions

Reaction Steps

3-Cyano-1-(4-methoxycarbonyl-benzoyl)-pyrrolo[1,2-a]quinoline (10 mg, 0.028 mmol) was disolved in a mixture of 5 mL of THF and 0.5 mL of ethyl alcohol and 1 mL of 2M NaOH was added and the mixture was stirred for 4 h at 50° C. The mixture was cooled to 0° C., acidified using 2N HCl and the resulting precipitate was collected, washed with cold ethyl alcohol and dried under vacuum (9.6 mg, 99%). 1H NMR (DMSO): 8.11–7.99 (m, 5H), 7.80–7.83 (m, 2H), 7.61–7.72 (m, 4H).

Provenance & Evidence