Ethylamine → HCID 2918886, compound

HRID 720488Notes

Reaction equation

HRID 720488 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[N:9]=[C:10]=[S:11].[CH2:12]([NH2:14])[CH3:13]>>[CH3:8][C:4]1[CH:5]=[CH:6][CH:7]=[C:2]([CH3:1])[C:3]=1[NH:9][C:10]([NH:14][CH2:12][CH3:13])=[S:11]

Participants

3

Reactant 2

HCID 6341EthylamineHCID 879762,6-Xylyl isothiocyanate

Product 1

HCID 2918886HCID 2918886, compound

Procedure

2,6-Dimethylphenyl isothiocyanate (16.3 g; 0.1 mol) was added dropwise to 110 mL of 70% aqueous ethylamine solution. The mixture was stirred for 1 hour at ambient temperature. Excess ethylamine was evaporated under a stream of nitrogen. The mixture was diluted with water (100 mL). The solid was collected by filtration and washed with water and dried to give 20.0 g of N-(2,6-dimethylphenyl)-N′-ethylthiourea.

Workup

  1. customExcess ethylamine was evaporated under a stream of nitrogen
  2. additionThe mixture was diluted with water (100 mL)
  3. filtrationThe solid was collected by filtration
  4. washwashed with water
  5. customdried

Sources & evidence

ORD record
ord-033567113dc448d9b000775976267523
Source dataset
uspto-grants-2006_11
Patent number
US07135492B2

Reaction notes

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