O-Allylhydroxylamine hydrochloride → HCID 9996464, compound

Participants

Reaction Steps

The title compound was prepared by coupling of 3-(4-fluorobenzyl)-3H-imidazo[4,5-c]pyridine-6-carboxylic acid and N-allyloxyamine hydrochloride under the same conditions as those in step (c) of example 1. 1H NMR (300 MHz, MeOH-d4) δ; 8.71 (s, 1H), 8.53 (s, 1H), 8.31 (s, 1H), 7.40–7.33 (m, 2H), 7.09–7.01 (m, 2H), 6.01–5.99 (m, 1H), 5.57 (s, 2H), 5.40–5.20 (m, 2H), 4.41 (d, 2H, J=6.0 Hz). LCMS (API-ES, M+H+): 327.0.1. HRMS calcd for C17H16FN4O2 (M+H) 327.1257. found 327.1248. HPLC: 100% purity.

Provenance & Evidence