N-(2-(4-Bromophenyl)propyl)propane-2-sulfonamide → HCID 21893383, compound

HRID 720570Notes

Reaction equation

HRID 720570 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([CH:8]([CH3:17])[CH2:9][NH:10][S:11]([CH:14]([CH3:16])[CH3:15])(=[O:13])=[O:12])=[CH:4][CH:3]=1.[CH:18]1([Mg]Cl)[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1>>[CH:18]1([C:2]2[CH:7]=[CH:6][C:5]([CH:8]([CH3:17])[CH2:9][NH:10][S:11]([CH:14]([CH3:16])[CH3:15])(=[O:13])=[O:12])=[CH:4][CH:3]=2)[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1

Participants

3

Reactant 2

HCID 9927066N-(2-(4-Bromophenyl)propyl)propane-2-sulfonamideHCID 178478990HCID 178478990, compound

Product 1

HCID 21893383HCID 21893383, compound

Procedure

The title product was prepared from the product of Example 27 as described in Example 15, Condition 2, with the exception that cyclohexylmagnesium chloride was used instead of cyclopentylmagnesium bromide.

Sources & evidence

ORD record
ord-bbb130c7afc2423ebf87c08f16336b9a
Source dataset
uspto-grants-2006_11
Patent number
US07135487B2

Reaction notes

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