p-Anisoyl chloride → HCID 21893450, compound

HRID 720600Notes

Reaction equation

HRID 720600 reaction equation
[NH2:1][CH2:2][CH2:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2[CH:15]=[CH:14][C:13]([CH:16]([CH3:25])[CH2:17][NH:18][S:19]([CH:22]([CH3:24])[CH3:23])(=[O:21])=[O:20])=[CH:12][CH:11]=2)=[CH:6][CH:5]=1.[CH3:26][O:27][C:28]1[CH:36]=[CH:35][C:31]([C:32](Cl)=[O:33])=[CH:30][CH:29]=1>>[CH3:26][O:27][C:28]1[CH:36]=[CH:35][C:31]([C:32]([NH:1][CH2:2][CH2:3][C:4]2[CH:5]=[CH:6][C:7]([C:10]3[CH:15]=[CH:14][C:13]([CH:16]([CH3:25])[CH2:17][NH:18][S:19]([CH:22]([CH3:24])[CH3:23])(=[O:21])=[O:20])=[CH:12][CH:11]=3)=[CH:8][CH:9]=2)=[O:33])=[CH:30][CH:29]=1

Participants

3

Reactant 2

HCID 7477p-Anisoyl chlorideHCID 21893565HCID 21893565, compound

Product 1

HCID 21893450HCID 21893450, compound

Procedure

The title compound was prepared following the method of Example 147 and using 1 mL of a stock solution of 0.6 g (1.8 mmol) of material from Example 50 and 13 μL (0.11 mmol) 4-methoxybenzoyl chloride. NMR was consistent with the proposed compound. Electrospray Mass Spectrum: M+1=495.

Sources & evidence

ORD record
ord-6effee418ea843b5861a5c6813182edc
Source dataset
uspto-grants-2006_11
Patent number
US07135487B2

Reaction notes

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