HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 11755954, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | HCID 10074423 | HCID 10074423 | — |
| Solvent | Tetrahydrofurane dichloromethane | HCID 21919333 | — |
| Product | HCID 11755954 | HCID 11755954 | — |
Reaction Steps
Prepared by reaction of 4-[8-(4-acetylamino-benzyl)-1-(2-fluorobenzyl)-2,6-dioxo-1,2,6,7-tetrahydro-purin-3-yl]-butyric acid with thionyl chloride in dichloromethane/tetrahydrofuran at room temperature and then reaction with excess methanol. Crystallization from methanol gave the product as a colorless solid. MS, m/z(M+H)=508.1986.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07135475B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-f7d52b47033a49e99cb656697fe0c484 |
| Source note | uspto-grants-2006_11 |