HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-4-fluorobenzene → 4-Fluoro-4'-methoxybiphenyl
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-4-fluorobenzene | HCID 9993 | — |
| Reactant | (4-Methoxyphenyl)boronic acid | HCID 201262 | — |
| Product | 4-Fluoro-4'-methoxybiphenyl | HCID 2758997 | 89% |
Reaction Steps
From 4-fluoro-bromobenzene and 4-methoxyphenyl boronic acid, yield 89%; mp 92-94° C. (lit.,2 94-96° C.); IR: 1504, 1276 and 1041; 1H NMR (400 MHz; CDCl3): 7.53-7.46 (4H, m), 7.11 (2H, t, J 8.7), 6.98 (2H, d, J 8.8) and 3.85 (3H, s); m/z (EI) 202 (95%, M+), 159 (100), 133 (90) and 69 (40)(Found: M+, 202.079. C13H11FO requires M, 202.079).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08828902B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-9c0b1640985042b3b9aac8440b7eb3b9 |
| Source note | uspto-grants-2014_09 |