HRID720866

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID21894476

17-Azido-3,6,9,12,15-pentaoxaheptadecan-1-amine

C12H26N4O5

结构：CN(C(=O)OCc1ccccc1)c1ccc(C(=O)N[C@@H](CCC(=O)NCCOCCOCCOCCN)C(=O)OC(C)(C)C)cc1

HCID66910315

未命名化合物

PRODUCTS

生成物

结构：CNc1ccc(C(=O)N[C@@H](CCC(=O)NCCOCCOCCOCCOCCOCCN)C(=O)OC(C)(C)C)cc1

HCID66933864

未命名化合物

PROCEDURE

实验过程

Compound 26 was synthesized by an analogous procedure as employed for compound 12, but using 1-amino-17-azido-3,6,9,12,15-pentaoxaheptadecane instead of 1-amino-11-azido-3,6,9-trioxaundecane in the first step of synthesis.

WORKUP

后处理

customin the first step of synthesis

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-57776329f171465b94437c39b22d8ba7
来源数据集: uspto-grants-2006_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07135550B2
来源说明: uspto-grants-2006_11

反应 SMILES

NCCOCCOCC[O:10][CH2:11][CH2:12][NH:13][C:14]([CH2:16][CH2:17][C@H:18]([NH:26][C:27]([C:29]1[CH:34]=[CH:33][C:32]([N:35](C(OCC2C=CC=CC=2)=O)[CH3:36])=[CH:31][CH:30]=1)=[O:28])[C:19]([O:21][C:22]([CH3:25])([CH3:24])[CH3:23])=[O:20])=[O:15].NCCO[CH2:51][CH2:52][O:53][CH2:54][CH2:55][O:56][CH2:57][CH2:58][O:59][CH2:60][CH2:61][O:62][CH2:63][CH2:64][N:65]=[N+]=[N-]>>[NH2:65][CH2:64][CH2:63][O:62][CH2:61][CH2:60][O:59][CH2:58][CH2:57][O:56][CH2:55][CH2:54][O:53][CH2:52][CH2:51][O:10][CH2:11][CH2:12][NH:13][C:14]([CH2:16][CH2:17][C@H:18]([NH:26][C:27]([C:29]1[CH:34]=[CH:33][C:32]([NH:35][CH3:36])=[CH:31][CH:30]=1)=[O:28])[C:19]([O:21][C:22]([CH3:25])([CH3:24])[CH3:23])=[O:20])=[O:15]