2-Aminophenol → HCID 178523776, compound

HRID 722025Notes

Reaction equation

HRID 722025 reaction equation
[CH2:1]([O:8][C:9]([NH:11][C@H:12]1[CH2:17][CH2:16][C@H:15]([C:18]([OH:20])=O)[CH2:14][CH2:13]1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=1[OH:28]>>[CH2:1]([O:8][C:9]([NH:11][C@H:12]1[CH2:13][CH2:14][C@H:15]([C:18]([NH:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=2[OH:28])=[O:20])[CH2:16][CH2:17]1)=[O:10])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 58012-AminophenolHCID 178523781HCID 178523781, compound

Product 1

HCID 178523776HCID 178523776, compound

Procedure

By treating trans-4-(benzyloxycarbonylamino)cyclohexanecarboxylic acid and 2-aminophenol in the same manner as in Reference Example 8-40, trans-4-benzyloxycarbonylamino-N-(2-hydroxyphenyl)cyclohexanecarboxamide was obtained.

Sources & evidence

ORD record
ord-b47f0b9db20e4e5bb6919b835b2fdc25
Source dataset
uspto-grants-2006_11
Patent number
US07138397B2

Reaction notes

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