HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Diamino-5-(2-methylpropyl)pyridine → 2,3-Diamino-5-(2-methylpropyl)pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Diamino-5-(2-methylpropyl)pyridine | HCID 21882710 | — |
| Reactant | HCID 21882727 | HCID 21882727 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | 2,3-Diamino-5-(2-methylpropyl)pyridine | HCID 21882710 | — |
| Product | HCID 21882727 | HCID 21882727 | — |
| Product | HCID 178493172 | HCID 178493172 | — |
Reaction Steps
Similarly to Example 1, 0.37 g of 3-(4-methoxypyridin-2-yl)propionic acid (starting material A1), 0.49 g of 2,3-diamino-5-(2-methylpropyl)pyridine (starting material D1) and 5 g of PPA (5 hours at 140° C. and chromatography using dichloromethane/methanol 30:1) give 0.151 g of the title compound of m.p. 111–113° C. The mass spectrum shows the molecular peak MH+ at 311.3 Da.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07138399B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-2e98196c7d8f4a6d99183244bc11e76a |
| Source note | uspto-grants-2006_11 |