HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 21882727, compound → HCID 21882727, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 21882727 | HCID 21882727 | — |
| Reactant | HCID 21882760 | HCID 21882760 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 21882727 | HCID 21882727 | — |
| Product | HCID 21882760 | HCID 21882760 | — |
| Product | 2-[2-(4-Methoxypyridin-2-yl)ethyl]-6-cyclohexylmethyl-3H-imidazo[4,5-b]pyridine | HCID 178493170 | — |
Reaction Steps
Similarly to Example 1, 0.275 g of 3-(4-methoxypyridin-2-yl)propionic acid (starting material A1), 0.28 g of 2,3-diamino-5-cyclohexylmethylpyridine (starting material E1) and 10 g of PPA (10 hours at 145° C. and chromatography using dichloromethane/methanol 15:1) give 0.183 g of the title compound of as a brownish oil. The mass spectrum shows the molecular peak MH+ at 351.4 Da.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07138399B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-1adb478d697b4fce9b4eb0a9ae307522 |
| Source note | uspto-grants-2006_11 |